No long-term animal studies have been performed to evaluate the carcinogenic potential of nystatin. Carcinogenisis, Mutagenisis, Impairment of Fertility If there is a lack of therapeutic response, KOH smears, cultures, or other diagnostic methods should be repeated. If symptoms of irritation develop, the patient should be advised to notify the physician promptly. Even if symptomatic relief occurs within the first few days of treatment, the patient should be advised not to interrupt or discontinue therapy until the prescribed course of treatment is completed.ģ. These medications are not for any disorder other than that for which they are prescribed.Ģ.
The patient should be instructed to use these medications as directed (including the replacement of missed doses). Patients using these medications should receive the following information and instructions :ġ. It is recommended that KOH smears, cultures, or other diagnostic methods be used to confirm the diagnosis of cutaneous or mucocutaneous candidiasis and to rule out infection caused by other pathogens. If irritation or sensitization develops, treatment should be discontinued and appropriate measures taken as indicated. Nystatin Ointment should not be used for the treatment of systemic, oral, intravaginal or ophthalmic infections. Nystatin Ointment is contraindicated in patients with a history of hypersensitivity to any of their components. Nystatin Ointment is not indicated for systemic, oral, intravaginal or ophthalmic use. Nystatin Ointment, is indicated in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida albicans and other susceptible Candida species. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses. This resistance is lost when the antibiotic is removed. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. However, other species of 47 75 17 Candida (C. On repeated subculturing with increasing concentrations of nystatin, Candida albicans does not develop resistance to nystatin.Generally, resistance to nystatin does not develop during therapy. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. krusei, Torulopsis glabrata, Tricophyton rubrum, T. Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C.
NYSTATIN CREAM DOSE SKIN
Nystatin is not absorbed from intact skin or mucous membrane.
Related/similar drugs fluconazole, nystatin topical, clotrimazole topical, ketoconazole topical, terbinafine, gentamicin topical, Diflucan Nystatin Ointment - Clinical Pharmacology
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